Immunometabolism Brain, Behavior, and Aging

Our lab investigates how immune driven metabolic pathways shape brain function, behavior, and vulnerability to disease across the lifespan. We focus on the kynurenine pathway of tryptophan metabolism as a key interface linking inflammation to cognitive function, affective states, and stress related behavioral outcomes.

Through interdisciplinary collaborations, we extend this work to neurodevelopmental disorders, seizures, substance use disorders, fatigue in older adults, and aging related health challenges, including research aimed at improving outcomes for older veterans. Our goal is to translate immunometabolic mechanisms into actionable targets for improving brain health and quality of life.