{"id":492,"date":"2023-12-11T20:07:51","date_gmt":"2023-12-11T20:07:51","guid":{"rendered":"https:\/\/labs.uthscsa.edu\/sayre\/?p=492"},"modified":"2023-12-11T20:07:51","modified_gmt":"2023-12-11T20:07:51","slug":"dr-sayres-laboratory-publishes-new-manuscript","status":"publish","type":"post","link":"https:\/\/labs.uthscsa.edu\/sayre\/2023\/12\/11\/dr-sayres-laboratory-publishes-new-manuscript\/","title":{"rendered":"Dr. Sayre\u2019s Laboratory Publishes New Manuscript"},"content":{"rendered":"<p>The Department of Neurosurgery is excited to announce the publication of a new manuscript from the laboratory of Naomi Sayre, PhD: \u201cLoss of LRP1 in adult neural stem cells impairs migration to ischemic lesions.\u201d<\/p>\n<p>In their study, the authors describe how the lipoprotein receptor family member, LRP1, regulates the expression of chemokine receptor CXCR4 to modulate neural stem cell migration toward stroke lesions. This novel discovery has implications related to stroke therapy, immune cell function, cancer cell migration, and neural stem cell response in Alzheimer\u2019s disease.<\/p>\n<p>Congratulations to Dr. Sayre and her team! You can read their article by <a href=\"https:\/\/academic.oup.com\/stmcls\/advance-article\/doi\/10.1093\/stmcls\/sxad034\/7142860\">visiting this link<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Department of Neurosurgery is excited to announce the publication of a new manuscript from the laboratory of Naomi Sayre, PhD: \u201cLoss of LRP1 in adult neural stem cells impairs migration to ischemic lesions.\u201d In their study, the authors describe how the lipoprotein receptor family member, LRP1, regulates the expression of chemokine receptor CXCR4 to [&hellip;]<\/p>\n","protected":false},"author":57,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"class_list":["post-492","post","type-post","status-publish","format-standard","hentry","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Dr. Sayre\u2019s Laboratory Publishes New Manuscript - Sayer\/Neurosurgery<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/labs.uthscsa.edu\/sayre\/2023\/12\/11\/dr-sayres-laboratory-publishes-new-manuscript\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dr. Sayre\u2019s Laboratory Publishes New Manuscript - Sayer\/Neurosurgery\" \/>\n<meta property=\"og:description\" content=\"The Department of Neurosurgery is excited to announce the publication of a new manuscript from the laboratory of Naomi Sayre, PhD: \u201cLoss of LRP1 in adult neural stem cells impairs migration to ischemic lesions.\u201d In their study, the authors describe how the lipoprotein receptor family member, LRP1, regulates the expression of chemokine receptor CXCR4 to [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/labs.uthscsa.edu\/sayre\/2023\/12\/11\/dr-sayres-laboratory-publishes-new-manuscript\/\" \/>\n<meta property=\"og:site_name\" content=\"Sayer\/Neurosurgery\" \/>\n<meta property=\"article:published_time\" content=\"2023-12-11T20:07:51+00:00\" \/>\n<meta name=\"author\" content=\"garzad11\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"garzad11\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/2023\\\/12\\\/11\\\/dr-sayres-laboratory-publishes-new-manuscript\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/2023\\\/12\\\/11\\\/dr-sayres-laboratory-publishes-new-manuscript\\\/\"},\"author\":{\"name\":\"garzad11\",\"@id\":\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/#\\\/schema\\\/person\\\/cf68c639093aa92edcaf142c245d0b6e\"},\"headline\":\"Dr. Sayre\u2019s Laboratory Publishes New Manuscript\",\"datePublished\":\"2023-12-11T20:07:51+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/2023\\\/12\\\/11\\\/dr-sayres-laboratory-publishes-new-manuscript\\\/\"},\"wordCount\":110,\"commentCount\":0,\"articleSection\":[\"News\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/2023\\\/12\\\/11\\\/dr-sayres-laboratory-publishes-new-manuscript\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/2023\\\/12\\\/11\\\/dr-sayres-laboratory-publishes-new-manuscript\\\/\",\"url\":\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/2023\\\/12\\\/11\\\/dr-sayres-laboratory-publishes-new-manuscript\\\/\",\"name\":\"Dr. Sayre\u2019s Laboratory Publishes New Manuscript - Sayer\\\/Neurosurgery\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/#website\"},\"datePublished\":\"2023-12-11T20:07:51+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/#\\\/schema\\\/person\\\/cf68c639093aa92edcaf142c245d0b6e\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/2023\\\/12\\\/11\\\/dr-sayres-laboratory-publishes-new-manuscript\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/2023\\\/12\\\/11\\\/dr-sayres-laboratory-publishes-new-manuscript\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/2023\\\/12\\\/11\\\/dr-sayres-laboratory-publishes-new-manuscript\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Dr. Sayre\u2019s Laboratory Publishes New Manuscript\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/#website\",\"url\":\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/\",\"name\":\"Sayer\\\/Neurosurgery\",\"description\":\"Naomi Sayre Lab\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/#\\\/schema\\\/person\\\/cf68c639093aa92edcaf142c245d0b6e\",\"name\":\"garzad11\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/119075b35e283cd979374f5618a69a942a23656c9d4470f6e4524afcb50d2f71?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/119075b35e283cd979374f5618a69a942a23656c9d4470f6e4524afcb50d2f71?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/119075b35e283cd979374f5618a69a942a23656c9d4470f6e4524afcb50d2f71?s=96&d=mm&r=g\",\"caption\":\"garzad11\"},\"url\":\"https:\\\/\\\/labs.uthscsa.edu\\\/sayre\\\/author\\\/garzad11\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Dr. Sayre\u2019s Laboratory Publishes New Manuscript - Sayer\/Neurosurgery","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/labs.uthscsa.edu\/sayre\/2023\/12\/11\/dr-sayres-laboratory-publishes-new-manuscript\/","og_locale":"en_US","og_type":"article","og_title":"Dr. Sayre\u2019s Laboratory Publishes New Manuscript - Sayer\/Neurosurgery","og_description":"The Department of Neurosurgery is excited to announce the publication of a new manuscript from the laboratory of Naomi Sayre, PhD: \u201cLoss of LRP1 in adult neural stem cells impairs migration to ischemic lesions.\u201d In their study, the authors describe how the lipoprotein receptor family member, LRP1, regulates the expression of chemokine receptor CXCR4 to [&hellip;]","og_url":"https:\/\/labs.uthscsa.edu\/sayre\/2023\/12\/11\/dr-sayres-laboratory-publishes-new-manuscript\/","og_site_name":"Sayer\/Neurosurgery","article_published_time":"2023-12-11T20:07:51+00:00","author":"garzad11","twitter_card":"summary_large_image","twitter_misc":{"Written by":"garzad11","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/labs.uthscsa.edu\/sayre\/2023\/12\/11\/dr-sayres-laboratory-publishes-new-manuscript\/#article","isPartOf":{"@id":"https:\/\/labs.uthscsa.edu\/sayre\/2023\/12\/11\/dr-sayres-laboratory-publishes-new-manuscript\/"},"author":{"name":"garzad11","@id":"https:\/\/labs.uthscsa.edu\/sayre\/#\/schema\/person\/cf68c639093aa92edcaf142c245d0b6e"},"headline":"Dr. Sayre\u2019s Laboratory Publishes New Manuscript","datePublished":"2023-12-11T20:07:51+00:00","mainEntityOfPage":{"@id":"https:\/\/labs.uthscsa.edu\/sayre\/2023\/12\/11\/dr-sayres-laboratory-publishes-new-manuscript\/"},"wordCount":110,"commentCount":0,"articleSection":["News"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/labs.uthscsa.edu\/sayre\/2023\/12\/11\/dr-sayres-laboratory-publishes-new-manuscript\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/labs.uthscsa.edu\/sayre\/2023\/12\/11\/dr-sayres-laboratory-publishes-new-manuscript\/","url":"https:\/\/labs.uthscsa.edu\/sayre\/2023\/12\/11\/dr-sayres-laboratory-publishes-new-manuscript\/","name":"Dr. Sayre\u2019s Laboratory Publishes New Manuscript - Sayer\/Neurosurgery","isPartOf":{"@id":"https:\/\/labs.uthscsa.edu\/sayre\/#website"},"datePublished":"2023-12-11T20:07:51+00:00","author":{"@id":"https:\/\/labs.uthscsa.edu\/sayre\/#\/schema\/person\/cf68c639093aa92edcaf142c245d0b6e"},"breadcrumb":{"@id":"https:\/\/labs.uthscsa.edu\/sayre\/2023\/12\/11\/dr-sayres-laboratory-publishes-new-manuscript\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/labs.uthscsa.edu\/sayre\/2023\/12\/11\/dr-sayres-laboratory-publishes-new-manuscript\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/labs.uthscsa.edu\/sayre\/2023\/12\/11\/dr-sayres-laboratory-publishes-new-manuscript\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/labs.uthscsa.edu\/sayre\/"},{"@type":"ListItem","position":2,"name":"Dr. Sayre\u2019s Laboratory Publishes New Manuscript"}]},{"@type":"WebSite","@id":"https:\/\/labs.uthscsa.edu\/sayre\/#website","url":"https:\/\/labs.uthscsa.edu\/sayre\/","name":"Sayer\/Neurosurgery","description":"Naomi Sayre Lab","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/labs.uthscsa.edu\/sayre\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/labs.uthscsa.edu\/sayre\/#\/schema\/person\/cf68c639093aa92edcaf142c245d0b6e","name":"garzad11","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/119075b35e283cd979374f5618a69a942a23656c9d4470f6e4524afcb50d2f71?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/119075b35e283cd979374f5618a69a942a23656c9d4470f6e4524afcb50d2f71?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/119075b35e283cd979374f5618a69a942a23656c9d4470f6e4524afcb50d2f71?s=96&d=mm&r=g","caption":"garzad11"},"url":"https:\/\/labs.uthscsa.edu\/sayre\/author\/garzad11\/"}]}},"_links":{"self":[{"href":"https:\/\/labs.uthscsa.edu\/sayre\/wp-json\/wp\/v2\/posts\/492","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.uthscsa.edu\/sayre\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/labs.uthscsa.edu\/sayre\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/labs.uthscsa.edu\/sayre\/wp-json\/wp\/v2\/users\/57"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.uthscsa.edu\/sayre\/wp-json\/wp\/v2\/comments?post=492"}],"version-history":[{"count":0,"href":"https:\/\/labs.uthscsa.edu\/sayre\/wp-json\/wp\/v2\/posts\/492\/revisions"}],"wp:attachment":[{"href":"https:\/\/labs.uthscsa.edu\/sayre\/wp-json\/wp\/v2\/media?parent=492"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/labs.uthscsa.edu\/sayre\/wp-json\/wp\/v2\/categories?post=492"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}