{"id":11,"date":"2024-07-11T18:19:33","date_gmt":"2024-07-11T18:19:33","guid":{"rendered":"https:\/\/labs.uthscsa.edu\/mak\/?page_id=11"},"modified":"2025-04-02T15:59:45","modified_gmt":"2025-04-02T15:59:45","slug":"research","status":"publish","type":"page","link":"https:\/\/labs.uthscsa.edu\/mak\/research\/","title":{"rendered":"Our Research"},"content":{"rendered":"

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Current Projects<\/h2>\n

[\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=”stretch_row”][vc_column width=”1\/4″][vc_single_image image=”31″ img_size=”large” css=””][\/vc_column][vc_column width=”5\/12″]

The genome integrity and epigenome of sperm from men with recurrent pregnancy loss (SpermRPL study)<\/h3><\/a>[vc_column_text css=””]This is a five-year NIH funded study that is relevant to public health because it addresses a major knowledge gap in our understanding of recurrent pregnancy loss by investigating male factor causes.\u00a0 This study will identify abnormalities in the quality of sperm and establish a new clinical paradigm to include diagnostic sperm testing of men with recurrent pregnancy loss.\u00a0 We will study sperm DNA fragmentation, sperm DNA methylation and sperm histone retention patterns using the latest molecular techniques.[\/vc_column_text][\/vc_column][vc_column width=”1\/3″] \n \n \n <\/i>\n <\/i>\n <\/span>

Publications<\/h3>\n <\/a>[\/vc_column][\/vc_row][vc_row full_width=”stretch_row”][vc_column width=”1\/4″][vc_single_image image=”31″ img_size=”large” css=””][\/vc_column][vc_column width=”5\/12″]

Project name<\/h3><\/a>[vc_column_text css=””]Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.[\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=”stretch_row”][vc_column width=”2\/3″][vc_column_text css=””]<\/p>\n
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[\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=”stretch_row”][vc_column width=”2\/3″][vc_column_text css=””]<\/p>\n

Past Projects<\/h2>\n

[\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=”stretch_row”][vc_column width=”1\/4″][vc_single_image image=”31″ img_size=”large” css=””][\/vc_column][vc_column width=”5\/12″]

Project name<\/h3><\/a>[vc_column_text css=””]Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.[\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=”stretch_row”][vc_column width=”1\/4″][vc_single_image image=”31″ img_size=”large” css=””][\/vc_column][vc_column width=”5\/12″]

Project name<\/h3><\/a>[vc_column_text css=””]Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.[\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” el_class=”margin-bottom-2″][vc_column width=”1\/4″][vc_single_image image=”31″ img_size=”large” css=””][\/vc_column][vc_column width=”5\/12″]

Project name<\/h3><\/a>[vc_column_text css=””]Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row full_width=”stretch_row”][vc_column width=”2\/3″][vc_column_text css=””] Current Projects [\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=”stretch_row”][vc_column width=”1\/4″][vc_single_image image=”31″ img_size=”large” css=””][\/vc_column][vc_column width=”5\/12″][vc_column_text css=””]This is a five-year NIH funded study that is relevant to public health because it addresses a major knowledge gap in our understanding of recurrent pregnancy loss by investigating male factor causes.\u00a0 This study will identify abnormalities in the quality of sperm […]<\/p>\n","protected":false},"author":94,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-11","page","type-page","status-publish","hentry"],"yoast_head":"\nOur Research - Mak Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/labs.uthscsa.edu\/mak\/research\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Our Research - Mak Lab\" \/>\n<meta property=\"og:description\" content=\"[vc_row full_width=”stretch_row”][vc_column width=”2\/3″][vc_column_text css=””] Current Projects [\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=”stretch_row”][vc_column width=”1\/4″][vc_single_image image=”31″ img_size=”large” css=””][\/vc_column][vc_column width=”5\/12″][vc_column_text css=””]This is a five-year NIH funded study that is relevant to public health because it addresses a major knowledge gap in our understanding of recurrent pregnancy loss by investigating male factor causes.\u00a0 This study will identify abnormalities in the quality of sperm […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/labs.uthscsa.edu\/mak\/research\/\" \/>\n<meta property=\"og:site_name\" content=\"Mak Lab\" \/>\n<meta property=\"article:modified_time\" content=\"2025-04-02T15:59:45+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/labs.uthscsa.edu\/mak\/research\/\",\"url\":\"https:\/\/labs.uthscsa.edu\/mak\/research\/\",\"name\":\"Our Research - 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