Huang Lab Publishes Review on Cytokine Storm Syndromes in Frontiers in Immunology
SAN ANTONIO, Texas — The Huang Lab announces the publication of a review titled “Into the storm: the imbalance in the yin‑yang immune response as the commonality of cytokine storm syndromes” in Frontiers in Immunology. The article appears in the Inflammation section, Volume 15. Frontiers
Authors include Amy Armstrong, Yuting Tang, Neelam Mukherjee, Nu Zhang, and Gang Huang of UT Health San Antonio and collaborating institutions. The article’s DOI is 10.3389/fimmu.2024.1448201. Frontiers
The review proposes that cytokine storm syndromes arise from a sustained tilt toward immune activation with inadequate contraction. It synthesizes evidence across conditions to explain hyperinflammation and organ injury. Frontiers
The authors note that steroids have broad utility yet limited impact on outcomes in many settings. They argue for stage‑specific, targeted approaches that restore immune balance. Frontiers
“This framework clarifies why patients diverge clinically and how precision therapies might correct the imbalance,” said Gang Huang, PhD. “We hope it guides better interventions.”
About the Huang Lab
The Huang Lab at UT Health San Antonio is a basic and translational cancer research group within the MD Anderson Mays Cancer Center at UT Health San Antonio. Our team integrates hematology and solid tumor biology with immunology and metabolism to uncover mechanisms and design interventions. We advance cell and biologic therapies, including CAR T‑cell approaches for solid tumors. We also conduct research in trauma and military health. We move discoveries toward clinical impact through product development and collaborations with clinicians and industry. Education and mentorship are core to our mission. We train students, postdoctoral fellows, and early‑career scientists in rigorous, multidisciplinary research. Together, we aim to deliver therapies and technologies that improve patient outcomes.